International Review of Ophthalmology ›› 2020, Vol. 44 ›› Issue (6): 413-418.doi: 10.3760/ cma.j.issn.1673-5803.2020.06.008

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Applications of fundus autofluorescence on diagnosis and visual prognosis assessment of idiopathic macular hole

Yue Huifang1,  Zhang Yunda2,  Zhang Ximei2   

  1. 1 Shanxi Medical University,  Taiyuan 030001,  China；  2 Department of Retina, Shanxi Eye Hospital,  Taiyuan 030002,  China
  • Received:2020-03-22 Online:2020-12-22 Published:2020-12-29
  • Contact: Zhang Ximei, Email: ximeizhang@sina.cn
  • Supported by:
    Technologies Research and Development Programs of Health Commission Foundation of Shanxi Province (2011058); Applied Basic Research Programs of Youth Technology Commission Foundation of Shanxi Province (201801D221014)

Abstract: Fundus autofluorescence (FAF) is a simple and non-invasive imaging modality. This technique based on the changes of lipofuscin and melanin within the retina,  gives insight into metabolic condition of retina. The FAF imaging of idiopathic macular hole (IMH) shows hyperautofluorescence corresponding to the hole area and surrounding hypoautofluorescent ring. The hyperautofluorescence can disappear or reduce due to a successful macular hole closure,  or can be persistent with an unclosed hole. FAF provides valuable information about diagnosis and follow-up of IMH,  combined with OCT has a great role both in vision prognosis,  understanding pathogenesis and anatomical and functional recovery. (Int Rev Ophthalmol,  2020,  44:  413-418)

Key words: fundus autofluorescence, idiopathic macular hole